LaPrade RF, Dragoo JL, Koh JL, Murray IR, Geeslin AG, Chu CR
Metformin is the first line of treatment in newly discovered T2D patients and was first demonstrated to influence gut microbiota composition in diet induced obese mouse models, where it resulted in enrichment of Akkermansia muciniphila (39, 40), a gut commensal showing beneficial effects on metabolism (41)
Multicellular self-assembled spheroidal model of the blood brain barrier
Acknowledgments This work was supported by a Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science (to DK) and by a Grant-in-Aid for Young Scientists from Japan Society for the Promotion of Science (to YT)
The peptide portion, GHK, has a strong affinity for copper ions