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A meta-analysis incorporating data from ten tirzepatide studies and involving over 6,800 participants found that tirzepatide at 15mg/weekly resulted in a 10% discontinuation rate due to adverse effects
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PubMed abstract No Spillover Effect of the Foreclosure Crisis on Weight Change: The Diabetes Study of Northern California (DISTANCE) Authors: Downing J
As a result of these findings, the collaborators suggested 'proglucagon 78-107 may be the incretin of the lower gut' (Holst, rskov, Vagn Nielsen, Schwartz)
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