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Beyond its indirect pro-osteoclastogenic effects, Th17 cells themselves express RANKL
10.2147/ijn.S182197 172 XuT.ZhuY.GeS.LiuS
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Reported biological activities in research include: Modulation of angiogenesis-related signaling pathways in experimental models Investigation of gastrointestinal protective mechanisms Influence on nitric oxide-related cellular signaling Study of oxidative stress and inflammatory response pathways Examination of connective tissue and extracellular matrix-related processes Investigation of neuronal response and neuroprotective mechanisms in laboratory models Current evidence remains limited, and further well-controlled clinical studies are required to establish long-term efficacy and safety in humans
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