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Both GSSG and GSSR can be catalytically reduced back to GSH by the NADPH-dependent GSH reductase and thioredoxin (Trx)/glutaredoxin (Grx) system, respectively

doi: 10.3390/ijms22073603 92 Fratta PasiniA

It is about the cumulative probability of contamination across multiple puncture events in a real laboratory environment

Among them, OPTN and NDP52 can directly bind ubiquitin-tagged mitochondria to the autophagosome through their LC3-interacting regions, even without the involvement of Parkin [132]

Accordingly, our models predicted a strong induction of several metabolic pathways in non-infected cells of COVID-19 patients based on an increased number of reactions active in the respective context-specific metabolic models, which was even more pronounced in patients with severe disease (Fig