Over the past few years, the conversation around GLP-1 receptor agonists has been dominated by extremes: dramatic weight loss in clinical trials, before-and-after transformations on social media, and a public discourse that has oscillated between miracle and backlash
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Here, we identify CNS sites activated by GIPR-Ab/GLP-1 and reveal key roles for both CNS GLP-1Rs and GIPRs to enable the full extent of weight loss and metabolic benefit
More study is needed before this can be confirmed, though (Savage, 2021)
Ferreiro E, Lanzillo M, Canhoto D, Carvalho da Silva AM, Mota SI, Dias IS, et al