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At 48 weeks, the least-squares mean percentage change in body weight in the retatrutide groups was -8.7% (1 mg), -17.1% (combined 4 mg), -22.8% (combined 8 mg), and an astounding -24.2% (12 mg), compared to -2.1% in the placebo group

Zhang Y, Fang X, Wei J, Miao R, Wu H, Ma K, et al

Addressing cost-related challenges and expanding research into new indications are crucial steps toward realizing the full potential of GLP-1 receptor agonists

EClinicalMedicine 3(72):102624 Jensen SBK, Srensen V, Sandsdal RM, Lehmann EW, Lundgren JR, Juhl CR et al (2024) Bone Health After Exercise Alone, GLP-1 Receptor Agonist Treatment, or Combination Treatment: A Secondary Analysis of a Randomized Clinical Trial