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Brian Cherry) at Arizona State University for help in the design & collection of HSQC-NMR data

These patients require extremely close monitoring, especially as rifampin is added to the regimen (expect a 2- to 5- fold increase in warfarin dosing requirements) and then when it is removed

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doi: 10.3389/fphys.2016.00206 136 BinionDGRafieePRamanujamKSFuSFisherPJRiveraMTet al

Further studies are warranted to design a formulation with increased bioavailability or target-oriented delivery, ascertain optimal dosage and route of administration, and conduct well-controlled, adequately powered, randomized clinical trials to determine the safety and efficacy of N-acetylcysteine in patients with COVID-19