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Most people start noticing an improvement in energy levels within 2-3 weeks

PMID 19832808

For those on a plant based diet, fortified foods like plant-based milk, breakfast, cereals, and nutritional yeast can help maintain healthy B12 levels

Phase 2 trial data (Jastreboff et al., NEJM 2023) demonstrated average weight reductions of approximately 1724% over 48 weeks notably higher than currently approved GLP-1 receptor agonists such as semaglutide, though direct comparisons are limited by differences in trial populations and designs

Many patients report that they feel upticks in their energy levels and are more active after starting their B12 regimen