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NICE Technology Appraisal guidance (TA875 for semaglutide/Wegovy and TA664 for liraglutide/Saxenda) recommends these medications for weight management in adults with: A body mass index (BMI) of at least 35 kg/m and At least one weight-related comorbidity (such as type 2 diabetes, hypertension, dyslipidaemia, obstructive sleep apnoea, or non-alcoholic fatty liver disease) For liraglutide (Saxenda), NICE TA664 specifies additional criteria including prediabetes (HbA1c 42-47 mmol/mol or fasting plasma glucose 5.5-6.9 mmol/L) or high risk of cardiovascular disease
From a clinical perspective, the love handle region can be considered an acceptable injection site if it contains adequate subcutaneous tissue and meets the standard requirements for subcutaneous injection
Locks in moisture to keep skin hydrated all day
Therapeutic management of metabolic dysfunction associated steatotic liver disease
Moore and June, 2020
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