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In this study, the effect of GLP-1 on basal MCR persisted after administration of theophyllinean adenosine receptor antagonistindicating that the vasodilatory effects of GLP-1 in human coronary arteries are unlikely to be mediated by adenosine
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Research shows this small molecule is an inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in cellular energy regulation and fat metabolism
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