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Current Opinion in Pharmacology

DOI Maquart FX, Pickart L, Laurent M, et al

ROS are highly reactive chemicals, enabling electron transfer from one molecule to another

Specifically, Ex-4 reduced the phosphorylation of JNK1/2 and c-Jun [40]

Alternate injection sites include the outer thigh or upper arm fatty tissue if rotating sites to prevent lipohypertrophy (tissue buildup from repeated injections)