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In animal studies, it affects angiogenesis (blood vessel formation), collagen organization, and growth factor modulation through pathways including EGR-1 gene upregulation
Garcia-Romo, G
GLP-1R activation has a significant effect on glycemic control in patients with T2DM through a variety of mechanisms, including stimulation of insulin secretion, inhibition of glucagon secretion, protection of -cells from apoptosis, slowing gastric emptying and increasing satiety (Drucker, 2006)
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