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By inhibiting calcium influx, exendin-4 reduces the calcium overload, which leads to apoptosis and excitation-induced neurotoxicity in RGCs, promoting RGC survival and function in DR (Wang et al., 2023)
S.GilesC.et al
We may try spreading out the number of days between doses from weekly to, say, every 10 days
It exists in virtually every cell, with the highest concentrations found in the liver (up to 10 mM), where it plays a central role in detoxification, and in the lungs, kidneys, and brain [2][3]
High and unstable blood glucose levels will promote tumor cell growth [48], so a reduction in glucose following L-carnitine treatment might have been beneficial to inhibit tumor growth in the CT26 tumor-bearing mice
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