A call for an interdisciplinary approach The clinical lessons of the past 25 years show that while achieving a weight loss threshold exceeding 10% is important for long-term fibromyalgia management, lifestyle modifications alone frequently fall short, Professor Ursini said
The expanded approval was based on data from the Phase III EoE KIDS trial, where 66% of children who received the higher dose Dupixent at tiered dosing regimens experienced histological disease remission after 16 weeks of treatment, compared to just 3% in the placebo group, per the press release
and records of intercepted drugs from Britain, Switzerland and Ireland
That matters for side effects, dose timing, surgery planning, and decisions about stopping or switching treatment
Intraclass differences and variations in pharmacokinetics are also possible explanations