6 For the first 3 months, patients were involved in implementing targeted lifestyle modifications including diet and exercise
Venous blood samples were obtained after patients had fasted overnight (12 h)
Lumit Cytokines Immunoassay offer no-wash, luminescent detection across a growing panel of proinflammatory targets including TNF-, IL-1, IL-6, IL-8, IFN- and more
El-Agroudy NN, Kurzbach A, Rodionov RN, OSullivan J, Roden M, Birkenfeld AL, et al
We hypothesize that the influence of SFN on the gut microbiota is at least partly related to the effects on their habitat, i.e., the gut such as (i) alleviation of oxidative stress and inflammation in the intestine, (ii) increase of the expression of tight junction proteins, preventing excessive intestinal permeability and invasion of luminal bacteria, and (iii) promotion of gut detoxification capability via increase of activity of phase II detoxification enzymes such as GSTs