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10.1002/etc.3093 9 AuldJ
The hub helps remove uncertainty by offering easy to understand breakdowns
Side-by-side comparison Factor Receptor targets Semaglutide GLP-1 only Tirzepatide GLP-1 + GIP Retatrutide GLP-1 + GIP + glucagon Liraglutide GLP-1 only Factor Half-life Semaglutide ~7 days Tirzepatide ~5 days Retatrutide ~6 days Liraglutide ~13 hours Factor Dosing frequency Semaglutide Once weekly Tirzepatide Once weekly Retatrutide Once weekly Liraglutide Once daily Factor Max studied dose Semaglutide 2.4 mg/week (SubQ)
Body-composition changes are another consideration like the rest of the class, some of the weight lost is lean tissue, which is why whether retatrutide makes you lose muscle is a common follow-up question
Stained sections were examined under an optical microscope
